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EGBET8 : Pharmaco-transcriptomic correlation analysis reveals novel ...

23 Sep 2024 —

... e.g. BET [8] and HDAC inhibitors [9].

Hippo signalling transduction converges on the LATS1/2-dependent phosphorylation of the transcriptional master YAP .... We perform integrative pharmaco-transcriptomic analysis by correlating drug response profiles of five pan-HDACis with transcriptomes of solid cancer cell lines ....

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e.g. BET [8], FreeSurfer [9]),. but none of them offer a fully satisfactory performance.

We propose taking advantage of these expert systems and unlabeled ....

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